Thursday, September 23, 2010
Injections May Relieve Drooling in Nerve-Damaged Kids
Thursday, September 23, 2010 | 
Posted by
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Botulinum toxin injections may temporarily relieve drooling in children with certain neurological conditions, a new European study has found.
Depending on its severity, drooling can lead to stigmatization and social neglect, numerous daily clothing changes, skin irritation around the mouth, aspiration pneumonia and dehydration, Dr. Arthur Scheffer of Radboud University Medical Center in Nijmegen, the Netherlands, and colleagues noted in a news release about their study.
In the study, Scheffer's team gave botulinum toxin injections to 131 children, average age 10.9 years, with cerebral palsy or other non-progressive neurological conditions, as well as moderate to severe drooling. Two months after the injections, the average drooling quotient had fallen to 15.5 (on a scale of zero to 100) from 28.8 at the start of the study. And, the study authors noted, 61 patients achieved a 50 percent reduction in drooling.
At the eight-month follow-up, the average drooling quotient was 18.7, according to the report in the September issue of the journal Archives of Otolaryngology -- Head & Neck Surgery.
Botulinum toxin injections have been used safely for years, according to the American Academy of Pediatrics. Side effects can include rash, whole-body muscle soreness, difficulty swallowing and weakness in the injected muscles, but they usually go away quickly, the AAP notes.
Depending on its severity, drooling can lead to stigmatization and social neglect, numerous daily clothing changes, skin irritation around the mouth, aspiration pneumonia and dehydration, Dr. Arthur Scheffer of Radboud University Medical Center in Nijmegen, the Netherlands, and colleagues noted in a news release about their study.
In the study, Scheffer's team gave botulinum toxin injections to 131 children, average age 10.9 years, with cerebral palsy or other non-progressive neurological conditions, as well as moderate to severe drooling. Two months after the injections, the average drooling quotient had fallen to 15.5 (on a scale of zero to 100) from 28.8 at the start of the study. And, the study authors noted, 61 patients achieved a 50 percent reduction in drooling.
At the eight-month follow-up, the average drooling quotient was 18.7, according to the report in the September issue of the journal Archives of Otolaryngology -- Head & Neck Surgery.
Botulinum toxin injections have been used safely for years, according to the American Academy of Pediatrics. Side effects can include rash, whole-body muscle soreness, difficulty swallowing and weakness in the injected muscles, but they usually go away quickly, the AAP notes.
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